| 11:00 PM | Local Programming |
| 11:29 PM | Saturday Night Live: Host January Jones; the Black Eyed Peas perform. |
| 1:02 AM | On the Rocks: The Search for America's Top Bartender: Eight bartenders compete for $100,000 and the title of ``America's Top Bartender.'' |
| 1:32 AM | Local Programming |
| 2:02 AM | Poker After Dark: Tom Dwan; Patrik Antonius; Howard Lederer; Eli Elezra; Ilari Sahamies; Phil Ivey. |
| 3:02 AM | In Wine Country - Earth-Friendly Wine Making: Going green and solar at a Napa winery; delectable wine country chocolates from former vintners. |
| 3:30 AM | Access Hollywood: The top entertainment stories of the week. |
| 4:30 AM | Extra |
| 5:30 AM | Hispanics Today: Latin entrepreneurs tackle issues. |
| 6:00 AM | Local Programming |
| 9:00 AM | Today: Tony Bennett's charter school; holiday buffet table. |
| 10:00 AM | The Chris Matthews Show: Journalists discuss whether President Obama will suffer long-term image damage. |
| 10:30 AM | Meet the Press: Secretary of State Hillary Clinton; Arne Duncan, Newt Gingrich; the Rev. Al Sharpton |
| 11:30 AM | Wall Street Journal Report With Maria Bartiromo: Jim Tisch discusses the state of today's economy; Mario Gabelli discusses the markets. |
| 12:00 PM | Local Programming |
| 1:00 PM | Cindy Crawford's Meaningful Beauty: Supermodel Cindy Crawford's skincare system. |
| 1:30 PM | Paid Programming |
| 2:00 PM | Local Programming |
| 6:30 PM | NBC Nightly News: The latest world and national news. |
| 7:00 PM | Football Night in America: With Bob Costas, Tony Dungy, Rodney Harrison and Tiki Barber. |
| 8:15 PM | NFL Football - New England Patriots at Indianapolis Colts |