Continuity: When the time machine crashes Wilbur is seen holding onto the steering wheel of the time machine, clearly detached from the time machine. At the next scene when Lewis and Wilbur are looking at the damage done to the time machine we see that the steering wheel is intact with the time machine.
Continuity: After Mildred schedules the interview for Lewis, she is holding the phone in her left hand. After Goob replaces the coffee in her right hand with his juice box, she turns into Lewis's room. The juice box is still in her hand but the phone has disappeared.
Continuity: During the memory scanner's wedding scene, Lewis recognizes Grandpa Bud because of the smile on the back of his balding head. In the next few glimpses, Bud has no hair on the back of his head, but when they get in the car together he does.
Continuity: After Doris creates her clone her hatband changes from purple to black, and then back to purple again.
Factual errors: When Doris sabotages the Memory Scanner, you see her turning a screw anticlockwise to remove it, but as the screw comes out you see it has a left-hand thread
Factual errors: Fire sprinklers don't work as depicted in the gymnasium scene. They are set off by heat (flames) not just smoke, and only the affected sprinkler releases water, not every sprinkler in the room or building.
Continuity: During the T-rex attack, the train and pizza dough disappear after they are used against the dinosaur.
Factual errors: When Lewis is explaining how the memory scanner works, he says that memories are stored in the cerebral cortex. They are actually stored in the limbic system and temporal lobe.