- Cate Blanchett was originally signed to play the role of Anna, but due to her second pregnancy she had to drop out of the film.
- Clive Owen played the role of Dan in the original stage production.
- At the beginning of filming, Natalie Portman gave 'Julia Roberts' a necklace that said "cunt" in honor of their characters' foul mouths. At the end of filming, Julia Roberts gave Natalie Portman a necklace that said "lil' cunt".
- The opera that Dan and Anna are late for and you can hear in the background is "Cosi Fan Tutte" - this also deals with themes of two couples who swap partners.
- The park Dan and Alice walk through is Postman's Park in London, near St Paul's Cathedral.
- The trailer includes several things that are not in the film. - different lighting when Anna and Dan kiss - shots of the driver of the car that hits Alice - a shot of Larry and Anna getting dressed - Larry telling Alice, "You women don't understand the territory, because you are the territory" - Anna asking Dan, "Why did you swear eternal love when all you wanted was excitement? Love bores you." Dan responds, "No, it disappoints me."
- Anna's exhibition is the only time all four characters are in the same room.
- Julia Roberts' character, Anna, was originally played on stage by Natasha Richardson.
- The original Broadway cast was: Anna Friel as Alice, Rupert Graves as Dan, Ciarán Hinds as Larry, and Natasha Richardson as Anna.
- When we last see her in bed, Julia Roberts' character, Anna, is reading Private Eye.
- Damien Rice, who sings the song "Blower's Daughter" on the film's soundtrack, Recorded a song for the movie also called "Closer" - but the song wasn't finished in time for the movies release. Another Rice song "Cold Water" can be heard in the film when Alice and Dan are walking around London after leaving the hospital.
- A segment of dialog from the movie was used for the titles of two Panic! At The Disco songs: "Lying is the Most Fun A Girl Can Have Without Taking Her Clothes Off" and "But It's Better If You Do."
- The photograph of an elderly couple which appears before Alice is photographed by Anna, and which appears also in Anna's exhibition, is a photograph of British philosophers Peter Geach and G. E. M. Anscombe.
- In 2006, both Clive Owen and Natalie Portman appeared in films about future dystopia's in Britain. V for Vendetta (2005) (Portman) and Children of Men (2006) (Owen).
- The original Broadway production of "Closer" by Patrick Marber opened at the Music Box Theater in New York on March 15, 1999, ran for 172 performances and was nominated for the 1999 Tony Award for the Best Play. Marber also wrote the screenplay for this filmed production.
>>> WARNING: Here Be Spoilers <<<
Trivia items below here contain information that may give away important plot points. You may not want to read any further if you've not already seen this title.
- SPOILER: The film stays very true to the original play upon which it is based, with one major exception. The play closed with Dan and Anna speaking briefly on a park bench, several years after Alice and Dan's breakup. Dan tells her that Alice had been hit by a car in New York City and had died, and that he was the only one authorities could find to identify her body. However, the film closes showing Alice alive, well and confidently walking the streets of Manhattan.
- SPOILER: Although Alice is alive at the end of the film, thus differentiating the film ending from that of the play, the very last shot as she's walking across a road in Manhattan is a pan/tilt up to a red "DON'T WALK" signal, thus hinting at the her fate as it is in the play.
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