The supporting cast for this film all took pay cuts in order to be in a movie with Bob Dylan.
The schedule board at the TV station is filled with titles of Dylan songs, including "It's Alright Ma" and "Hurricane".
Bob Dylan and Larry Charles used pseudonyms for the screenplay because of the film's title.
In the Midas Judas building where Uncle Sweetheart works, the listing of offices in that building includes Dr. Benway, the doctor from William Burrough's Naked Lunch.
Charlie Sexton, who was sitting to Bob Dylan's right, was once Bob's guitarist while on tour.
In Dylan's first scene, where he is released from prison, he is wearing a wig. He liked it so much that he continued to wear it for various occasions, including his appearance at the Newport Folk Festival in August 2002.
Filmed in just twenty days. Utilizing digital video, Larry Charles was able to shoot up to eight pages of script a day.