Footage from the 1967 film Poor Cow (1967) (Ken Loach's directorial debut) is featured as flashbacks of Wilson (Terence Stamp) with his baby daughter and wife.
The first song heard in The Limey (1999) is "The Seeker" by The Who. During the 1960s one of The Who's two managers was Christopher Stamp, Terence Stamp's brother.
The relationship between Wilson and Ed echoes the relationship between the literary characters of Don Quixote de la Mancha and Sancho Panza, as seen in many movies, such as Man of La Mancha (1972) and the classic Russian film Don Kikhot (1957).
Ann-Margret shot scenes with Peter Fonda, as his ex-wife. These scenes were not used in the completed film, as the director felt he had already established Fonda's creepiness adequately.
The original screenplay envisioned the main character would be played by Michael Caine.
Luis Guzmán's character is prominently seen wearing a t-shirt of Che Guevara. Director Steven Soderbergh would later direct a two-part film about Che.