The strange chessboard in the opening scene is the "Game of Ur," a game from ancient Mesopotamia whose rules have been lost.
Dan O'Bannon had been working on the screenplay for Screamers (1995) as early as 1981. The October 10, 1984 draft credits Michael Campus as co-writer. It is unknown whether Campus also intended to direct.
When Joe Hendricksson and Ace Jefferson enter the N.E.B. base, Becker uses his knife to hit a pipe, the code is 3 shorts and 3 longs. This spells out "SO" in Morse code.
In the original short story by P. K. Dick the plot takes place on Earth, instead of Sirius 6B. Originally, Screamers were designed by Americans troops hiding in the moon to destroy the Russian Army after the Soviet Union had completely wiped out the United States.