| Brian Benben | ... | Roger Henderson |
 | Mary Stuart Masterson | ... | Penny Henderson |
| Ned Beatty | ... | General Walt Whalen |
| George Burns | ... | Milt Lackey |
| Scott Michael Campbell | ... | Billy |
| Brion James | ... | Bernie King |
| Michael Lerner | ... | Lieutenant Cross |
| Michael McKean | ... | Rick Rochester |
| Jeffrey Tambor | ... | Walt Whalen, Jr. |
| Stephen Tobolowsky | ... | Max Applewhite |
| Christopher Lloyd | ... | Zoltan |
| Larry Miller | ... | Herman Katzenback |
| Anita Morris | ... | Claudette Katsenback |
| Corbin Bernsen | ... | Dexter Morris |
| Rosemary Clooney | ... | Anna |
| Bobcat Goldthwait | ... | Wild Writer |
| Robert Walden | ... | Tommy |
| Dylan Baker | ... | Jasper |
| Billy Barty | ... | Himself |
| Tracy Byrd | ... | Himself |
| Candy Clark | ... | Billy's Mother |
| Anne De Salvo | ... | Female Writer |
| Jennifer Dundas | ... | Deirdre |
| Bo Hopkins | ... | Billly's Father |
| Robert Klein | ... | Father Writer |
| Harvey Korman | ... | Jules Cogley |
| Joseph Lawrence | ... | Frankie Marshall (as Joey Lawrence) |
| Peter MacNicol | ... | Son Writer |
| Bridgett Newton | ... | Member, The Miller Sisters |
| Amy Parrish | ... | Member, The Miller Sisters |
| Nina Repeta | ... | Member, The Miller Sisters |
| Frank Trimble | ... | Member, The Dead Tones |
| Kevin Scott Warner | ... | Member, The Dead Tones |
| Frank J. Aard | ... | Rollerskating Penguin |
| Ellen Albertini Dow | ... | Organist |
| Mary Boucher | ... | Soapbox Girl |
| Doug Chambers | ... | Drummer |
| Tina Corsini | ... | Betty Boop |
| Jim David | ... | Biff Blaster |
| Deacon Dawson | ... | Happy, Peter Lorre Villain |
| Hadley Eure | ... | 'Paprika' Actress |
| J. Don Ferguson | ... | Johnny Ace, Hard Boiled Dick (as Don Ferguson) |
| Wilbur Fitzgerald | ... | 'Tortured' Actor |
| Keith Flippen | ... | Space Cadet Jimmy |
| Paul 'Mousie' Garner | ... | Double bass performer (as Mousie Garner) |
| Randell Haynes | ... | Difficult Actor / Interrogator |
| Mark Joy | ... | Jack Granite, Man's Man |
| Rebecca Koon | ... | Ma, Mildred's Mother |
| Gary Kroeger | ... | Gork, Son of Fire |
| Tammy Lauren | ... | In the Mood Bandleader |
| Marguerite MacIntyre | ... | Bubble Bath Announcer |
| Lori Anne Mahl | ... | Mildred, Johnny Ace Secretary (as Lori Mahl) |
| Charles Marsh | ... | Upside-Down Yodeler |
| Jim McKeny | ... | Tom McCallum |
| Madison McKoy | ... | Cab Calloway |
| Rod McLachlan | ... | Black Whip, Granite's Dog |
| Marc McPherson | ... | Maynard |
| Patt Noday | ... | Sherwood Smith |
| Richard K. Olsen | ... | Pa, Lt. Cross Actor |
| Donna Peters | ... | 'Gork' Actress |
| Robert D. Raiford | ... | Ben Butter (as Robert Raiford) |
| Robin Dale Robertson | ... | Temperamental Actor |
| Jack Sheldon | ... | Ruffles Reed |
| Frank Terrio | ... | Duck |
| Gary Anthony Williams | ... | Dr. Ashton-Reeves |
| Brad Moranz | ... | Dancer #1 |
| Jennifer Moranz | ... | Dancer #2 |
| Deborah DeFrancisco | ... | Dancer #3 (as Deborah De Francisco) |
| Lynn Raley | ... | Dancer #4 |
| Leanne Reese | ... | Dancer #5 |
| Crystal Williams | ... | Dancer #6 |
| Dixie Wilson | ... | Dancer #7 |
| Barry Bell | ... | Cop #1 |
| Gabe Caggiano | ... | Cop #2 |
| Anthony Christian | ... | Cop #3 |
| Lou Criscuolo | ... | Cop #4 |
| Michael Harding | ... | Cop #5 (as Mike Harding) |
| John Keenan | ... | Cop #6 |
| Mark Marshall | ... | Cop #7 |
| Mark Jeffrey Miller | ... | Cop #8 |
| Michael P. Moran | ... | Cop #9 |
| Mike O'Brien | ... | Cop #10 |
| Bob Sayer | ... | Cop #11 |
| Rock Taulbee | ... | Cop #12 |
| Robert C. Treveiler | ... | Cop #13 (as Robert Treveiler) |
| Hank Troscianiec | ... | Cop #14 |
| Harold Bergman | ... | Affiliate |
| Rita Butler | ... | Affiliate's Wife |
| Dave Hager | ... | Laughing Man |
| Kim Head | ... | Waitress |
| Scott Hilley | ... | Drunk Affiliate |
| Ed Lillard | ... | Loud Affiliate |
| Leighann Lord | ... | Morgana |
| Joann Luzzatto | ... | P.A. |
| Eric Paisley | ... | Enthusiastic Affiliate |
| D. Anthony Pender | ... | Operator, Revolving Stage (as Anthony Pender) |
| Jeffrey Pillars | ... | Nerdy Stagehand |
| Steve Rassin | ... | Page |
| Pam Stone | ... | Dottie |
| Leslie Truman | ... | Woman in Audience |
| Norm Woodel | ... | Announcer |
| rest of cast listed alphabetically: |
| Jamison Jones | ... | Pilot (uncredited) |
| Michele Seidman | ... | Radio Actress 5-B (uncredited) |
