Martin Scorsese was originally set to direct but dropped out. In fact, it was Scorsese who recruited screenwriter Richard Price to write a draft. According to an interview with Neal Gabler, Price said, "[Scorsese] felt like he had already 'done' [Night in the City] in all his other films... there was no challenge for him." It would be another six years before Producer/Director Irwin Winkler and Robert De Niro became interested in making the film.
In the original draft, Harry Fabian (Robert De Niro) is killed by a stab wound at the end of the movie, which stayed true to the original Jules Dassin film's ending. This was changed later during production.
This was the first of two films written by Richard Price that Martin Scorsese left the helm as director. The second film was 'Clockers' in which Scorsese turned over the project to Spike Lee so he could instead direct 'Casino'.
Cameo: [Vincent Pastore] In the first scene in the boxing gym you can spot him more than once in the background behind Robert De Niro. He is in street clothes with a big cigar in his mouth "sparring" with a boxer.