Revealing mistakes: During the hallucination sequence in the cave, the pyrotechnic charges underneath the mushroom-shaped rock are visible as it elevates, as is the wire lifting it up.
Anachronisms: The introductory story is set in 1967, but exterior shots of the streets shows a VW Rabbit and a Plymouth Volare, both 1970s cars.
Continuity: The recording which Emily listens to of Eddie's first drug induced tank trip isn't the same as the original dialog. Some of the wording is changed and the loud primal "grunt" which alarmed both Mason and Arthur has been replaced with a sound much more resembling that of a monkey.
Continuity: While Arthur takes Eddie's blood and Mason is yelling at him, the position of the bloody rag used to wipe Eddie's face clean as well as the EEG wiring changes positions between shots.
Continuity: When the Brujo tells Eccheverria that he'll allow Eddie to participate in the ceremony he walks off. In only a matter of seconds he's far enough away that they have to run quite a distance to catch up to him to ask him some further questions. There's no way he could have gotten that far in the short span of time between his walking off and their pursuit of him.